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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKACG
All Species:
16.97
Human Site:
S15
Identified Species:
33.94
UniProt:
P22612
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22612
NP_002723.2
351
40434
S15
K
D
T
E
Q
E
E
S
V
N
E
F
L
A
K
Chimpanzee
Pan troglodytes
XP_528314
453
51759
S117
K
D
T
E
Q
E
E
S
V
N
E
F
L
A
K
Rhesus Macaque
Macaca mulatta
O62846
209
24077
Dog
Lupus familis
XP_867543
351
40605
S15
K
K
G
S
E
V
E
S
V
K
E
F
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P05132
351
40552
S15
K
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
Rat
Rattus norvegicus
P27791
351
40601
S15
K
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6U1I9
432
48872
M70
Q
P
Q
E
P
E
L
M
N
A
N
P
S
P
P
Frog
Xenopus laevis
Q6GPN6
434
49096
L72
P
P
Q
E
P
E
L
L
N
E
N
S
S
P
P
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
M71
P
P
Q
D
V
E
L
M
N
S
N
P
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12370
353
40820
T17
K
K
V
D
A
A
E
T
V
K
E
F
L
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P21137
404
46327
D52
I
L
D
D
P
V
E
D
F
K
E
F
L
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
Q41
L
Q
Q
R
Q
Q
Q
Q
Q
Q
R
Q
H
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
54.7
78.9
N.A.
81.4
81.4
N.A.
N.A.
35.6
35.9
35.5
N.A.
74.7
N.A.
61.3
N.A.
Protein Similarity:
100
76.8
57.2
88.5
N.A.
91.4
91.7
N.A.
N.A.
53.7
53.6
53.3
N.A.
86.1
N.A.
73.7
N.A.
P-Site Identity:
100
100
0
60
N.A.
60
60
N.A.
N.A.
13.3
13.3
6.6
N.A.
40
N.A.
33.3
N.A.
P-Site Similarity:
100
100
0
66.6
N.A.
73.3
73.3
N.A.
N.A.
20
13.3
20
N.A.
60
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
0
9
0
0
0
42
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
9
25
0
0
0
9
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
34
25
42
59
0
0
9
59
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
59
0
0
0
% F
% Gly:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
34
0
0
0
0
0
0
0
42
0
0
0
0
50
% K
% Leu:
9
9
0
0
0
0
25
9
0
0
0
0
59
0
0
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
25
17
25
0
0
0
0
% N
% Pro:
17
25
0
0
25
0
0
0
0
0
0
17
0
25
25
% P
% Gln:
9
9
34
0
25
25
9
9
9
9
0
9
0
9
17
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
25
0
0
0
42
0
9
0
9
25
0
0
% S
% Thr:
0
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
9
17
0
0
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _